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Dihydroxy-acid dehydratase
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Dihydroxy-acid dehydratase : ウィキペディア英語版
Dihydroxy-acid dehydratase

In enzymology, a dihydroxy-acid dehydratase () is an enzyme that catalyzes the chemical reaction
:2,3-dihydroxy-3-methylbutanoate \rightleftharpoons 3-methyl-2-oxobutanoate + H2O
Hence, this enzyme has one substrate, 2,3-dihydroxy-3-methylbutanoate, and two products, 3-methyl-2-oxobutanoate (α-ketoisovaleric acid) and H2O.
This enzyme participates in valine, leucine and isoleucine biosynthesis and pantothenate and coenzyme A (CoA) biosynthesis.
== Nomenclature ==

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2,3-dihydroxy-3-methylbutanoate hydro-lyase (3-methyl-2-oxobutanoate-forming). Other names in common use include
* acetohydroxyacid dehydratase,
* alpha,beta-dihydroxyacid dehydratase,
* 2,3-dihydroxyisovalerate dehydratase,
* alpha,beta-dihydroxyisovalerate dehydratase,
* dihydroxy acid dehydrase,
* DHAD,
* and 2,3-dihydroxy-acid hydro-lyase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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